Statistical Analysis of Lipid Profiles Associated with Coronary Heart Disease in Erbil City-Iraq

Authors

  • Dler hussein kadir Department of Statistics, College of Administration and Economics, Salahaddin University-Erbil, Kurdistan Region, Iraq
  • Karzan Abdullah School of Medicine, University of Kurdistan Hewler, KRG, Iraq, Zanco Private Hospital, Kurdistan Regional Government. Erbil-Iraq
  • Aziz Muazafar jafaar Department of Endocrinology, Ministry of Health, Kurdistan Regional Government, Erbil-Iraq ,Department of Endocrinology, Iraqi Board for Medical Specializations, Erbil, Iraq
  • Rebaz Hamza Salih Ministry of Health, Kurdistan Regional Government. Erbil-Iraq ,PAR Private Hospital, Kurdistan Regional Government. Erbil-Iraq
  • Shukur Wasman Smail Department of Biology, College of Science, Salahaddin University-Erbil, Iraq ,Department of Medical Microbiology, College of Science, Cihan University-Erbil, Kurdistan Region, Iraq
  • Gashaw Qasim Rahman School of Medicine, University of Kurdistan Hewler, KRG, Iraq
  • Harem Khdir Awla Department of Biology, College of Science, Salahaddin University-Erbil, Iraq
  • Zhikal Omar Khudhur Biology Education Department, Tishk International University, Erbil, Iraq

Keywords:

Cardiovascular disease, Cholesterol, Coronary Heart Diseases, Lipid Profile, Triglycerides

Abstract

Background and objectives: Coronary heart disease (CHD) is one of the most prevalent diseases
worldwide. The primary risk factor for coronary heart disease (CHD) lies in the presence of hypertension,
elevated levels of triglycerides (TG), total cholesterol (TC), and low-density lipoprotein (LDL) in the
bloodstream. Furthermore, a reduction in high-density lipoprotein (HDL) levels is linked to an elevated risk
of cardiovascular disease-related mortality.
The current retrospective study was undertaken to evaluate the alterations in the lipid profile of patients with
CHD.
Methods: The current survey involved collecting data from 867 patients diagnosed with acute or severe
CHD, with an average age of 48.38± 0.503. In addition, the study included 850 healthy controls whose
average age was 47.22±1.234. The serum levels of TC, HDL, LDL, and TG were obtained from Zanko Hospital
in Erbil city, Iraq. The comparison between the recorded parameters of healthy controls and patients was
conducted using the t-test function in GraphPad Prism 6.0.
Results: The lipid profile consisted of measurements for TC, LDL, HDL, and TG. The TC levels were notably
higher in cases of CHD in individuals under 40 years old compared to controls. Moreover, there was a notable
rise in TG levels among individuals with CHD aged 40-60, in contrast to the control group. Conversely, there
was no significant difference in the levels of HDL and LDL between the cases and control group.
Conclusions: There was a significant difference in TC and TG levels between cases and controls in certain
groups, while other lipid profiles did not show significant changes.

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Published

2023-09-20